Over here we usually don't cover big distances (300-400 km, so there's n/p doing it in one go). I know many people who love making stops &c, but I prefer getting out of a car only on destination.
The biggest trip I've driven is night drive to Germany (600 km) during one night, conducting all the buissiness that I had to do over the day and night drive back; needless to say w/o any sleep over that period. And before you ask- I never had an accident in my life (only one 'controlled' spin).